| ID | Sequence | Length | GC content |
|---|---|---|---|
| AGCAUUUGAAGCUGCAGUCCUGAAAACCAUGCAGGCCGGAAGAGUAGAU… | 1395 nt | 0.3849 | |
| UAAGUGUACAUGCUUAGGCCUUCUGAAGCAGCAUUUGAAGCUGCAGUCC… | 1058 nt | 0.3629 |
This gene encodes a member of the heat shock factor (HSF) family of transcriptional activators for heat shock proteins. This gene is a candidate gene for azoospermia, since it localizes to a region of chromosome Y that is sometimes deleted in infertile males. The genome has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
A collaborative exercise in human samples demonstrated that the HSFY1 was evaluated in a preliminary study but gave inconsistent results during singleplex testing and was not included in the final validated semen pentaplex [Haas et al. DOI:10.1016/j.fsigen.2012.10.011].