Basic Information

Symbol
HSPB6
RNA class
mRNA
Alias
Heat Shock Protein Family B (Small) Member 6 PPP1R91 Hsp20 Heat Shock Protein, Alpha-Crystallin-Related, B6 Protein Phosphatase 1, Regulatory Subunit 91 Heat Shock Protein Family B Member 6 Heat Shock 20 KDa-Like Protein P20 Heat Shock Protein Beta-6 FLJ32389 Heat Shock Protein Family B (Small) Member B6 Epididymis Secretory Sperm Binding Protein Epididymis Luminal Protein 55 HEL55 HspB6
Location (GRCh38)
19:35754566-35758079
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_144617.3
Sequence length
1460.0 nt
GC content
0.6274

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-433.60 kcal/mol
Thermodynamic ensemble
Free energy: -459.59 kcal/mol
Frequency: 0.0000
Diversity: 407.80
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..........(((((((.((((.((((......((((..((((((((.....)))))))).))))...((....((((((.((((((..((.(((((((.(..((((((......(((((((((((((((((((((((((((((((((..(((((((.(....(((((.((((((...((((((((((.(((((....(((((...(.(((((((......).)))))).)....))))).....))))))))..(((....((((.(((((....)))))...))))))).)))))))))))))...))))).(((((....)))))..).)))))))..((((.(((.((((..(((((((.((.((((...(((.(((((..((.....)).))))))))....))))))))))))))))).)))))))..((((((.(((((((..(((.((((.((....(((.((((((((.((((.((((..((....))...)).)).)))).)))))))))))..)).....((((((((....)))))))).........((.((......)).)).(((.((((.((((.(((((.(...((((...))))....).)))))..))))))))..)))...((((...))))....)))).)))...))))...........))).))))))..............))))))...((.........)).........)))))))))).......))))..........))))).))))).)))(((((.......((.......(((((((.....)))......)))).......)).........))))).......))))))).)))))))............................((((((.....)))))).(((.(((..............)))..))).(((......................(((.((((.((...........)).)))))))......((((((((..((((((...((....))..(((....))).(((((.....(((.......))).(((...((((..(((..............)))..))))...)))...........))))).......))))))..))))))))..((((.(((.((...........((.((((.(((.................))).)))).)))).))).)))))))...........(((....)))........))..))))))....(.((((.....)))).).................))))))...)).......)))))))))))))))...(((((......((((....))))..........(((.........)))..............))))).....(((...((((..((.......))..))))....)))..
Thermodynamic Ensemble Prediction
...,,,..,.(((((((.((((.((((......((((,.((((((((,...,)))))))).|}||,,{{{....{,,((,{(((({{.{(({({((((({({{,,,{((,..{{{(((((((((((((({(((((({(((((((((((..({((..,||.{|.|||{|,|||||{,,.{{,,{{{({(,(((((.{{.(((((...{.(((((({......),}))))).,....))))).....)))))})).,|..,||.||||,|||||},,})))},...))))}))}||||||||||||,...|||||.||,||,,||||||,{{({({,(,{{.,{{{,.{||.|{{{,,|||{|||}||}.||,||,|||.||{,..}|||,}}}}},,)))))}}..}}))})))))}))}))))).))}}}}}.,}||||({(,((((,..,,,}|||,}||....(((.((((((((.((((.((,{..((....))...},.)).)))).)))))))))))..}}.....((((((((....)))))))).........((,((,,,,..|,.}}.{{|.{{({.{(({.(((((.(...((((...|})}......))))}..|||||}||..}||,,.{{{,.,,|||,....}}}}.}}}...,,,|...........||,.,,,}}|||............,,}}},...,{.........,|.........}))||}}}}}.......}}}}..........}}}}}.))))}.,)}|},}},......|,........,..(((.....)))......,|||.......,,..........,))),..,,..,,}))),.}}})))).,........................,,((((((.....)))))).|{,.{|{............,,))}..)))}})}},},,,,...............{{,{((((.((...........)).)))))}}......((((((((..((((((...{,....,,..(((....))).(((((.....,,{.....,,|||.,,,...((((..(((..............)))..))))..}))),..........))))).......))))))..)))))))).....,..................||.((((.(((.................))).)))).}}))||}}|}},||,...,,.......,,,....,||.............,}}}.....{.{{{(,....}}}),).......,))},,,,..}}},..............))))))))))})}}}...,|||,......((((....)))),|........,{{,........,}}.............,}|||.....,|||,..{(((..{{......,))..))))...,)),..

Transcripts

ID Sequence Length GC content
NM_144617.3 NCBI
ACUGCAACGCGGAGGAGCAGGAUGGAGAUCCCUGUGCCUGUGCAGCCGU… 1460 nt 0.6274
Summary

This locus encodes a heat shock protein. The encoded protein likely plays a role in smooth muscle relaxation. [provided by RefSeq, Jan 2012]

Forensic Context

A study in humans demonstrated that the HSPB6 was identified as a potential diagnostic biomarker for sepsis, showing a consistent mRNA and corresponding protein expression pattern in a nine-quadrant analysis of serum from sepsis patients compared to healthy controls [Wang et al. DOI:10.2147/IDR.S380137].