Basic Information

Symbol
IGHG1
RNA class
mRNA
Alias
Immunoglobulin Heavy Constant Gamma 1 (G1m Marker) Constant Region Of Heavy Chain Of IgG1 Immunoglobulin Heavy Constant Gamma 1 Immunoglobulin Gamma 1 (Gm Marker) Ig Gamma-1 Chain C Region KOL Ig Gamma-1 Chain C Region NIE Ig Gamma-1 Chain C Region EU Ig Gamma-1 Chain C Region
Location (GRCh38)
14:105736343-105743071
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
-
Sequence length
- nt
GC content
-
Summary

Enables Fc-gamma receptor I complex binding activity. Involved in antibody-dependent cellular cytotoxicity and complement-dependent cytotoxicity. Located in extracellular space. Part of IgG immunoglobulin complex. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that single-cell RNA sequencing of peripheral blood mononuclear cells from an irradiated patient revealed significant alterations in cell type proportions and gene expression profiles compared to healthy controls [Yan et al. DOI:10.3892/etm.2025.12846].