Immunoglobulin Superfamily Member 6
DORA
Down-Regulated By Activation (Immunoglobulin Superfamily)
Immunoglobulin Superfamily, Member 6
Protein DORA
IgSF6
Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in cell surface receptor signaling pathway and immune response. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in human skin demonstrated that the IGSF6 gene, classified as part of the inflammatory/immune response, was significantly up-regulated in thermally injured tissue compared to normal skin during the early wound repair process [Greco et al. DOI:10.1016/j.burns.2009.06.211].