Basic Information

Symbol
IL32
RNA class
mRNA
Alias
Interleukin 32 TAIF NK4 TAIFb TAIFd Tumor Necrosis Factor Alpha-Inducing Factor Natural Killer Cell Transcript 4 Natural Killer Cells Protein 4 Interleukin-32 Interleukin-32 Small Interleukin-32 Theta Interleukin-32 Eta IL-32alpha IL-32delta IL-32gamma IL-32beta TAIFa TAIFc IL-32
Location (GRCh38)
16:3064301-3082192
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001376923.1
Sequence length
818.0 nt
GC content
0.5697

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-298.60 kcal/mol
Thermodynamic ensemble
Free energy: -312.74 kcal/mol
Frequency: 0.0000
Diversity: 175.56
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((((.(((((((.((((...((..(((.(.(((((((.(((((((((((((((((((((........(((((((((.((.((((.(..((((((((.(((...........((((..((((.(((...((((...((((.....(((((..........((((...))))))))).....))))...))))...))).)))).....))))...........))).))))))))..).)))).)))))))))))......)))))))..(((..(((((((..((((((.(((........)))))).)))......(((....))).....(((((..((((((.(((.(......).))).))).)))....)))))))))))).))).))))))).)))))))((.((..((((.(((((((...)))))).).)))))).))((((((..((..((((((..((.((.((.((.(((...(((...(((((((((((..((((((((....))))))))..))))).........(((((((.((((.(((((((((((..(((((.((........))..)))))..)))))))..)))).....)))).)))))))......(((.(((...))).))))))).))..)))...)))..)))).)).))...)))))).)).))))))...))))))).).))).))..)))).)))...))))...)))))....((((.((((........(((((.((.....)).)))))))))..))))..........................
Thermodynamic Ensemble Prediction
.(((((.(((((((.((((.,.(,..(((.(,(((((((.(((((((((((((((((((((,.......(((((((((.{{,((((.(..((((((((.(((.,.........((((..((((.(((...((((.,.((((.....(((((..........((({...})))})))).....)))).}.))))...))).)))).....)))).........,.))).))))))))..).)))).)}))))))))).....,)))))))..(((..(((((((..((((((.(((........)))))).)))....,,(((....))}.}...(((((.,((((((.(((.(.,,...),))).))).))).,..)))))))))))).))).))))))).)))))))|{,{({{(|{,{{({(({{..,)})))).)}))).||,,.((((((..((..((((((..((.((((((((((.....{{.....{{({.(((((..((((((((....))))))))..)))))})).....,(((((((.((((.(((((((((((..(((((.((........))..)))))..)))))))..)))).....)))).)))))))......(((.(({...})).)))...,.)))))))))}.,)}),,.{{{....}}})))))).)}.))))))..,))))))).).))).)},.)))).)))...))))...)))))....{(((.((((.....,,.(((((,{{.....)).))}))))))..))))..........................

Transcripts

ID Sequence Length GC content
NM_001012631.4 NCBI
AGAGACUCCCACCCCAGCUCAGAGGGAGCAGGGGCCCAGCCAGGGACGG… 929 nt 0.5780
NM_001012632.3 NCBI
AGACUGCGUGCAGAAGGUGACUGUCUCAGUGGAGCUGGGUCAUCUCAGG… 841 nt 0.5731
NM_001012633.4 NCBI
AGAGACUCCCACCCCAGCUCAGAGGGAGCAGGGGCCCAGCCAGGGACGG… 691 nt 0.5789
NM_001012634.4 NCBI
AGACUGCGUGCAGAAGGUGACUGUCUCAGUGGAGCUGGGUCAUCUCAGG… 758 nt 0.5831
NM_001012635.4 NCBI
AGACUGCGUGCAGAAGGCCUUGGCUCCUUGAACUUUUGGCCGCCAUGUG… 726 nt 0.5840
NM_001012636.2 NCBI
GCCUUGGCUCCUUGAACUUUUGGCCGCCAUGUGCUUCCCGAAGGUCCUC… 743 nt 0.5680
NM_001012718.4 NCBI
AGAGACUCCCACCCCAGCUCAGAGGGAGCAGGGGCCCAGCCAGGGACGG… 865 nt 0.5815
NM_001308078.4 NCBI
AGACUGCGUGCAGAAGGUGACUGUCUCAGUGGAGCUGGGUCAUCUCAGG… 956 nt 0.5753
NM_001369587.3 NCBI
AGAGACUCCCACCCCAGCUCAGAGGGAGCAGGGGCCCAGCCAGGGACGG… 1003 nt 0.5852
NM_001369588.3 NCBI
AGAGACUCCCACCCCAGCUCAGAGGGAGCAGGGGCCCAGCCAGGGACGG… 1000 nt 0.5850
Showing 1 to 10 of 19 entries
Summary

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.