This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation. [provided by RefSeq, Jul 2008]
Forensic Context
A study in humans analyzing leukocyte gene expression profiles from severe burn patients identified the ANKRD23 as a top sustained increasing gene (SIG) with expression rising from the healthy state through the late recovery phase (>400 hours post-injury), classifying it as a biomarker for burn recovery [Xu et al. DOI:10.1159/000493451].