Kallikrein Related Peptidase 10
NES1
PRSSL1
Normal Epithelial Cell-Specific 1
Protease Serine-Like 1
Kallikrein-10
Breast Normal Epithelial Cell Associated Serine Protease
Kallikrein 10 Protein 12
Kallikrein 10 Protein 13
Kallikrein 10 Protein 1
Kallikrein 10 Protein 2
Kallikrein 10 Protein 3
Kallikrein 10 Protein 4
Kallikrein 10 Protein 5
Kallikrein 10 Protein 7
Kallikrein 10 Protein 8
Kallikrein 10 Protein 9
Kallikrein 10
EC 3.4.21.74
EC 3.4.21.-
EC 3.4.21
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded protein is secreted and may play a role in suppression of tumorigenesis in breast and prostate cancers. Alternate splicing of this gene results in multiple transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]
Forensic Context
A study in humans demonstrated that the KLK10 mRNA, used for vaginal secretion (VS) identification, showed low-level cross-reaction in semen, menstrual blood, and saliva samples [Yu et al. DOI:10.1016/j.fsigen.2025.103416].