Keratin 25
KRT25A
Type I Inner Root Sheath-Specific Keratin-K25irs1
Keratin, Type I Cytoskeletal 25
Keratin 25, Type I
Cytokeratin-25
Keratin-25A
CK-25
K25A
K25
Type I Inner Root Sheath Specific Keratin 25 Irs1
Keratin 25A
Keratin-25
KRT24IRS1
ARWH3
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21. [provided by RefSeq, Jul 2009]
Forensic Context
A study in humans identified the KRT25 as one of the top five downregulated genes in burn patient skin tissue compared to normal skin, based on differential expression analysis of a transcriptomic dataset [Yang et al. DOI:10.3389/fgene.2021.781589].