Lysosomal Protein Transmembrane 5
Lysosomal-Associated Multitransmembrane Protein 5
Lysosomal-Associated Transmembrane Protein 5
Lysosomal Multispanning Membrane Protein 5
Retinoic Acid-Inducible E3 Protein
Lysosomal Associated Multispanning Membrane Protein 5
CD40-Ligand-Activated Specific Transcripts
Human Retinoic Acid-Inducible E3 Protein
KIAA0085
CLAST6
This gene encodes a transmembrane receptor that is associated with lysosomes. The encoded protein, also known as E3 protein, may play a role in hematopoiesis. [provided by RefSeq, Feb 2009]
Forensic Context
A study in humans demonstrated that the LAPTM5 is the most connected hub gene in a prefrontal co-expression network centered on LINC01268, a lincRNA associated with suicide by violent means and aggression [Punzi et al. DOI:10.1101/257188]. This network, which was strongly preserved across control groups, is implicated in modulating the inflammatory response by macrophages, highlighting a biological process potentially underlying the observed behavioral phenotypes.