This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking and quality control. [provided by RefSeq, Oct 2008]
Forensic Context
A study in mice demonstrated that the LMAN2 mRNA expression level was significantly higher in the cecal ligation and puncture (CLP) group compared to the Sham group [Yang et al. DOI:10.1038/s41598-025-06463-2].