Basic Information

Symbol
LY6G6C
RNA class
mRNA
Alias
Lymphocyte Antigen 6 Family Member G6C NG24 C6orf24 G6c Lymphocyte Antigen 6 Complex Locus Protein G6c Lymphocyte Antigen 6 Complex, Locus G6C Chromosome 6 Open Reading Frame 24 Lymphocyte Antigen-6 G6C G6C
Location (GRCh38)
6:31718648-31721746
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_025261.3
Sequence length
893.0 nt
GC content
0.5510

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-260.00 kcal/mol
Thermodynamic ensemble
Free energy: -274.44 kcal/mol
Frequency: 0.0000
Diversity: 175.34
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((.(((((........))))))))).((((((.(((((((((((((....(.((((...........((((((((.(((..((((.....((.((((((((((((((((.....))))(((((.....)))))......(((((.((.(((......))))).)))))..(((((....)))))...)))).))))))))))((((.((......)).)))).....))))..))).)))))))).....)))).)..)))))).))).((((.(((((....)).))))))).............(((.((.((((.((........))..))))))))).....(((((((((((.((((.((((.....((((....((((((..(((................)))..))))))....)))))))))))).))))..(((.((((..(((..(((.................))).)))..)))).)))............((((((.((...))...)))))).............(((.((((((((..........((((......)))).....((((...(((((((((.(((((.....................((((......))))..((((((.((((((......)).)))).))))))...........((............))...........))))).))))..))))).))))...))))))))))).....))))))).(((((((((.(((.....)))))).......)))))).))))))))))...........(((((((.(((.(((.............((((((.............))))))))).)))...))))))).
Thermodynamic Ensemble Prediction
((((.(((((........))))))))).((((((.((((((({((({(,,....((((.,....,,,..((((((((.{{{..{{{{,,...((.((((((((((((((.((((..((((.,,.....))))..)},),.}(((((.((.(((......))))).)))))..(((((....)))))...))))}})))))))))((((.((......)).)))).....)))}.,}}}.)))))))).....,|||{|,{||}|||.}}}.((((.(((((....)).))))))).............(({{((.((({.{{........}}..})),))))).....{{{{{{{|||{,||||}||||.....((((.,..((((((..(((....{.....,.....,}}..))))))....))))),}))))).}|||..((({((((..(((..(((.................))).)))..)))).,}}}}.....}||..((((((.{{...}}...))))))..,,.........(((.((((((((..........((((......))))....,{..{,{{,,{{,((((.(((((.....................((((......))))..,(((((.((((((......)).)))).)))))|,..........||............},.,,........))))).))))..})))).,))),,.))))))))))}..,,,))))))}.(((((((((.(((.....)))}))...,.,,)))))).))))))))))...........(((((((.{((,({{.............((((((.............))))))}}}.))),..))))))).

Transcripts

ID Sequence Length GC content
NM_025261.3 NCBI
AGAGCUGGAUCCUUGAAAAUCUACUCUAUCAGCUGCUGUGGUUGCCACC… 893 nt 0.5510
Summary

LY6G6C belongs to a cluster of leukocyte antigen-6 (LY6) genes located in the major histocompatibility complex (MHC) class III region on chromosome 6. Members of the LY6 superfamily typically contain 70 to 80 amino acids, including 8 to 10 cysteines. Most LY6 proteins are attached to the cell surface by a glycosylphosphatidylinositol (GPI) anchor that is directly involved in signal transduction (Mallya et al., 2002 [PubMed 12079290]).[supplied by OMIM, Mar 2008]

Forensic Context

A study in mice demonstrated that the LY6G6C was the second most increased gene in female versus male E7.0 embryos, with a +6.4 Log2FC differential expression, and encodes a lymphocyte antigen 6 complex locus G6C protein involved in signal transduction [Boschen et al. DOI:10.1002/Bdr2.2292].