Basic Information

Symbol
MAP1LC3B2
RNA class
mRNA
Alias
Microtubule Associated Protein 1 Light Chain 3 Beta 2 ATG8G Microtubule-Associated Proteins 1A/1B Light Chain 3 Beta 2 Microtubule-Associated Protein 1 Light Chain 3 Beta 2 MAP1A/MAP1B Light Chain 3 B-Like MAP1A/MAP1B LC3 B-Like Microtubule-Associated Proteins 1A/1B Light Chain 3B-Like Protein Microtubule-Associated Proteins 1A/1B Light Chain 3B-Like
Location (GRCh38)
12:116548105-116576606
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001085481.3
Sequence length
818.0 nt
GC content
0.4670

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-224.10 kcal/mol
Thermodynamic ensemble
Free energy: -240.11 kcal/mol
Frequency: 0.0000
Diversity: 212.39
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
....((((...))))........(((((((((((((((...))).))).(.((((......)))).)((((((((..(((((....)))))..........(((..((....))..))).(((((((.((..(((((((.................)))).))).(((....)))..)).)))))))..((((..((.....)).))))..))))))))..(((.(((((...((((((((........))).............((((((((............(((......)))...........)))))))).((((((((((.....((.((..(.(((((((.(.....(((((((......(((.....)))......)))))))...).))))))).)..)).))))))))))))(((((...(((...(((((........))))))))....)))))....)))))..((((..((((((((((..((((.(((....)))))))(((.....)))...................(((((((((......((((((....((((...)))).)))))))))))))))....((((((......))))))........))))))))))...))))..((((((....((.(((((.((((....((.((((((.....)))))).))...))))))))).)).)))))).....))))).))).(((((((....)))))))......(((((((.((((((...)))))).)))))))......)))))))))...............
Thermodynamic Ensemble Prediction
((((((((,,{||||..({{{,{((,((((((((,,,,.,})))}))}.{.((((......)))).}((((((((..(((((....))))).,.........((.{(({{{{||,,....{{{,,||}{||}{,|||||,,...............||||{}||,{,....,}))..}}.))))))}..((((..{{.....)}.))))..))))))))..,||}||||{.||{{{{.{((........))),............((((((((,.{{,,,{{{..,,})))}}},),...........)))))))},((((((((((.....((.((..{.(((((((.{.....(((((((.,,...(((.....)))....,,)))))))...}.))))))).)..}).)})))))))))),|((({.{((({..,,,,,..))))}.,))))|||,,..{|||{{,,,{,|||,,((((..((((((((({,{(({{.{||,...}}}}|||{{,...,.||,{{,......,,,.......(((((((({......{(((((....((({...}))).,})))})))))))))....,{|||{.,,..,))}}))}}}}}...))))))))))...})))..((((({.,{{,{.(((((.((((....((.((((((.....)))))).))...))))))))).})})))))).,,,,|}}}},}}..(((((((....))))))).,},}}{((((((.((((({...}))))).))))))}....}}))))....................

Transcripts

ID Sequence Length GC content
NM_001085481.3 NCBI
GCAAGGCUCGCAGCCACCUCUCGGGAGUGCAGGGCCAGAUCCUGUGCCA… 818 nt 0.4670
Summary

Predicted to enable microtubule binding activity; phosphatidylethanolamine binding activity; and ubiquitin protein ligase binding activity. Predicted to be involved in cellular response to nitrogen starvation and macroautophagy. Predicted to be located in several cellular components, including cytoplasmic vesicle; endomembrane system; and microtubule. Predicted to be active in autophagosome membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human pediatric sepsis patients identified the MAP1LC3B2 as exhibiting decreased polyadenylation in viral compared to bacterial infection samples, classifying it among candidate genes with differential poly(A) tail length variation [He et al. DOI:10.1186/s12879-025-11078-z].