Enables 4 iron, 4 sulfur cluster binding activity. Involved in mitochondrial small ribosomal subunit assembly. Located in nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice demonstrated that acute alcohol exposure during neurulation induces rapid transcriptomic changes in the rostroventral neural tube, with METTL17, a gene encoding methyltransferase activity, being significantly down-regulated (-0.24 Log2FC) 4 hours post-exposure [Boschen et al. DOI:10.1016/J.Alcohol.2022.09.001].