This gene encodes a protein highly similar to the mouse meiosis-specific nuclear structural 1 protein. The mouse protein was shown to be expressed at the pachytene stage during spermatogenesis and may function as a nuclear skeletal protein to regulate nuclear morphology during meiosis. [provided by RefSeq, Oct 2008]
Forensic Context
A study in humans demonstrated that the MNS1 gene was downregulated in the lungs as part of the inhibited cell cycle pathway in sepsis patients [Pinheiro da Silva et al. DOI:10.1111/jcmm.17938].