Membrane Spanning 4-Domains A7
CD20L4
CFFM4
MS4A8
Membrane-Spanning 4-Domains Subfamily A Member 7
Four-Span Transmembrane Protein 2
CD20 Antigen-Like 4
4SPAN2
High Affinity Immunoglobulin Epsilon Receptor Beta Subunit
Membrane-Spanning 4-Domains, Subfamily A, Member 7
CD20/Fc-Epsilon-RI-Beta Family Member 4
CD20/FC-Epsilon-RI-Beta Family Member 4
This gene encodes a member of the membrane-spanning 4A gene family, members of which are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns in hematopoietic cells and nonlymphoid tissues. This family member is associated with mature cellular function in the monocytic lineage, and it may be a component of a receptor complex involved in signal transduction. This gene is localized to 11q12, in a cluster of other family members. At least four alternatively spliced transcript variants encoding two distinct isoforms have been observed. [provided by RefSeq, Jul 2008]
Forensic Context
A longitudinal mRNA expression analysis in post-mortem human blood samples demonstrated that the MS4A7 was identified as a protein coding gene with a negative coefficient in a post-mortem interval (PMI) prediction model, indicating its down-regulated expression pattern after death contributed to PMI estimation [Antiga et al. DOI:10.1038/s41598-021-96095-z].