Basic Information

Symbol
MT-CO2
RNA class
mRNA
Alias
Mitochondrially Encoded Cytochrome C Oxidase II COX2 MTCO2 COII CO2 Cytochrome C Oxidase Polypeptide II Cytochrome C Oxidase Subunit II Cytochrome C Oxidase Subunit 2 Cytochrome C Oxidase II EC 7.1.1.9 EC 1.9.3.1 COXII
Location (GRCh38)
MT:7586-8269
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Time since deposition estimation
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
-
Sequence length
- nt
GC content
-
Summary

Contributes to cytochrome-c oxidase activity. Predicted to be involved in mitochondrial electron transport, cytochrome c to oxygen and positive regulation of vasoconstriction. Located in mitochondrial inner membrane. Part of respiratory chain complex IV. Biomarker of Huntington's disease and stomach cancer. [provided by Alliance of Genome Resources, Jul 2025] CIViC Summary for MT-CO2 Gene

Forensic Context

A study in humans demonstrated that the MT-CO2 is a potential time-marker transcript, as it was one of 11 continuously upregulated transcripts identified during the degradation of bloodstains stored at 4°C over 168 days [Zhang et al. DOI:10.1016/j.forsciint.2024.111930].