Basic Information

Symbol
MYL7
RNA class
mRNA
Alias
Myosin Light Chain 7 MYLC2A MYL2A Myosin Regulatory Light Chain 2, Atrial Isoform Myosin, Light Polypeptide 7, Regulatory Myosin, Light Chain 7, Regulatory Myosin Regulatory Light Chain 7 Myosin Light Chain 2a MLC-2a MLC2a
Location (GRCh38)
7:44138864-44143179
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_021223.3
Sequence length
612.0 nt
GC content
0.5719

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-214.30 kcal/mol
Thermodynamic ensemble
Free energy: -225.56 kcal/mol
Frequency: 0.0000
Diversity: 204.70
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
(.((((((...((((((.((.((((((((.(((((((((((((((((((....((((..(((((...)))))..)).(((((.((((((.....)).))))........(.(((((((...((........)).))))))).).((((((.(((((..(((......)))..)))))....(((((...)))))(((..((((.((.(((((((.....))))..))).)).))))..))).(.((((((...))).))).)..))))))..)))))))......))).))))))))))...)))...(.(((((((((((...(((......)))...(((..((((((..((.....((((.(.((((.((.....)))))).).))))...)).))))))..)))..).)))))))))).)....)))......))))))))..)).))))))((((....))))(((((....(((.(((.((((((..........((((...)))).((((.((.((((.((...(.((....)).)...)).).))).)).)))).)))))).))).)))))))).............)))))))..........
Thermodynamic Ensemble Prediction
,.(((((({..((((((.((.(((((((({{{{,(((((((((((((((,,,{((((..(((((...)))))..,,.{||||.,({(|(,,,,.}}..))},,.,{||.{|(((((((...{(,.......)).))))))},}.((({((.(((((..(({......)))..)))))....(((((...)))))(((..((((.((.{((((((....,))),.}))).)).))))..))).(.((({({...))}.})).)..}}})))..}}))))|.,,...|||.||}}}}}|||...|||...({((({{(((((,...(((......)))}.{((({.((({{{..|||,|,,||{|.,||||,.||,},,.))},.,)))))))}}|}|.,})))).,)))..,.)))))))))}....,}))}.,.,..})))))))..)).)))))){{((.,.,))}}(((((....(((.(((.((((((,|....,.,}((((...)))).((((.((.{{({.({...{.{{....}).,...)},),))),)).)))).)))))).))).)))))))).............})))))}..........

Transcripts

ID Sequence Length GC content
NM_021223.3 NCBI
GACAGCAGCCACACCUCUGCAGAGAGAAUGGCCAGCAGGAAGGCGGGGA… 612 nt 0.5719
Summary

Predicted to enable calcium ion binding activity. Predicted to be involved in cardiac muscle tissue development and heart contraction. Located in A band. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans developed a 17-plex endpoint RT-PCR assay for forensic organ tissue identification, where the MYL7 was validated as a specific mRNA marker for heart tissue identification [Lindenbergh et al. DOI:10.1007/s00414-013-0895-7].