This gene is a member of the NEUROD family of basic helix-loop-helix transcription factors. The encoded protein may be involved in the development and differentiation of the nervous system. [provided by RefSeq, Nov 2012]
Forensic Context
A study in humans demonstrated that the NEUROD6 is an mRNA marker used in targeted massively parallel sequencing assays for brain tissue identification [Hanson & Ballantyne DOI:10.3390/genes8110319]. This assay, along with other targeted MPS approaches, has been successfully applied for high-resolution forensic transcriptome analyses, including body fluid and tissue identification, demonstrating high specificity and sensitivity [Haas et al. DOI:10.1016/j.fsigen.2021.102486].