NK3 Homeobox 1
NKX3.1
BAPX2
NKX3A
Homeobox Protein NK-3 Homolog A
Homeobox Protein Nkx-3.1
NK3 Transcription Factor Related, Locus 1 (Drosophila)
NK3 Transcription Factor Related, Locus 1
NK Homeobox (Drosophila), Family 3, A
NK3 Transcription Factor Homolog A
NK Homeobox, Family 3, A
NKX3
This gene encodes a homeobox-containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jan 2012]
Forensic Context
A study in humans established a method using coding single nucleotide polymorphisms (cSNPs) within semen-specific mRNA markers, including the NKX3-1 which contains the cSNP rs11781886, to identify the semen contributor in mixed body fluid stains [Liu et al. DOI:10.1016/j.fsigen.2021.102483].