2''-5''-Oligoadenylate Synthetase Like
P59OASL
TRIP14
2'-5'-Oligoadenylate Synthetase Like
OASL1
59 KDa 2'-5'-Oligoadenylate Synthase-Like Protein
2'-5'-Oligoadenylate Synthase-Like Protein
Thyroid Receptor-Interacting Protein 14
2'-5'-OAS-Related Protein
TR-Interacting Protein 14
2'-5'-OAS-RP
P59 OASL
TRIP-14
59 KDa 2'-5'-Oligoadenylate Synthetase-Like Protein
2'-5'-Oligoadenylate Synthetase-Like
P59-OASL
OASLd
Enables DNA binding activity and double-stranded RNA binding activity. Involved in several processes, including interleukin-27-mediated signaling pathway; negative regulation of viral genome replication; and positive regulation of RIG-I signaling pathway. Located in cytosol; nucleolus; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in mice identified the OASL as a specifically expressed core differentially expressed gene (DEG) in the 12-hour post-wound group, where it was down-regulated, and its expression pattern is associated with wound age estimation [Zhu et al. DOI:10.1016/j.legalmed.2021.101982].