Olfactory Receptor Family 2 Subfamily V Member 1
OST265
Olfactory Receptor 2V1
OR2V1P
Olfactory Receptor, Family 2, Subfamily V, Member 1 Pseudogene
Olfactory Receptor, Family 2, Subfamily V, Member 1
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. [provided by RefSeq, Jul 2008]
Forensic Context
A study in humans identified the OR2V1 mRNA as hypermethylated in the postmortem nucleus accumbens of subjects with alcohol use disorder compared to controls, with a mean methylation level of 0.623 in cases versus 0.274 in controls [Liu et al. DOI:10.3390/genes13060958].