Basic Information

Symbol
OST4
RNA class
mRNA
Alias
Oligosaccharyltransferase Complex Subunit 4, Non-Catalytic Dolichyl-Diphosphooligosaccharide--Protein Glycosyltransferase Subunit 4 Oligosaccharyltransferase Complex Subunit 4 (Non-Catalytic) Oligosaccharyltransferase 4 Homolog (S. Cerevisiae) Oligosaccharyltransferase 4 Homolog
Location (GRCh38)
2:27070470-27071685
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001134693.2
Sequence length
442.0 nt
GC content
0.5023

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-129.40 kcal/mol
Thermodynamic ensemble
Free energy: -137.04 kcal/mol
Frequency: 0.0000
Diversity: 68.06
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.((((.(((((((.(((((.((.(((.((((.(((...(((...(((.((.(((((.((...(((((((.((((...................)))).)))).))).)).))))))).)))...)))..)).).)))).))))).))))).)))..))))))))......(((((((((((.....((..((((((..((((...(.(((((((..((((((((((((.((((((...................)))))))))))..........................((((....)))).......)))))))))))))).)..)))).))))))..)).....))))).)))))).....(((((((((((.((((....................)))).))))(((((........))))).)).))))).....
Thermodynamic Ensemble Prediction
.{(((.(((((((.(((((.((.(((.((((.(((...(((...(((.((.(((((.((...(((((((.((((..,........,.......)))).)))).))).)).))))))).)))...)))..)).).)))).))))).))))).)))..))))))))......((((((((((({{...((..((((((..((((...{.(((((((.,{({(((((((((.((((((..................,)))))}))))).}}.......................((((....))))........,,,}),))))))).}..)))).))))))..))....,))))).))))))..,..((((((,,,,,.((({....................}}||.|||}{((((........}}))},))})),)},....

Transcripts

ID Sequence Length GC content
NM_001134693.2 NCBI
CUCUGACUUCGGGCUUGUUCGCUGGUGGCGUCGGAGCCGAGCCGGACUG… 442 nt 0.5023
Summary

Involved in protein N-linked glycosylation via asparagine. Part of oligosaccharyltransferase complex A and oligosaccharyltransferase complex B. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans characterized the platelet transcriptome in patients with acute myocardial infarction (MI) using RNA-seq and identified the OST4 as a highly expressed, platelet-enriched marker in both ST-segment elevation MI (STEMI) and non-STEMI (NSTEMI) subtypes [Eicher et al. DOI:10.3109/09537104.2015.1083543].