Phosphatidylinositol-5-Phosphate 4-Kinase Type 2 Gamma
PIP5K2C
Phosphatidylinositol-4-Phosphate 5-Kinase, Type II, Gamma
Phosphatidylinositol 5-Phosphate 4-Kinase Type II Gamma
Phosphatidylinositol 5-Phosphate 4-Kinase Type-2 Gamma
PI(5)P 4-Kinase Type II Gamma
PIP4KII-Gamma
EC 2.7.1.149
FLJ22055
Phosphatidylinositol-5-Phosphate 4-Kinase, Type II, Gamma
Phosphatidylinositol 4-Phosphate 5-Kinase
EC 2.7.1
Enables 1-phosphatidylinositol-4-phosphate 5-kinase activity and identical protein binding activity. Involved in 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate biosynthetic process; negative regulation of insulin receptor signaling pathway; and positive regulation of autophagosome assembly. Located in several cellular components, including autophagosome; cytosol; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
A study in human traumatic brain injury tissue identified the PIP4K2C as part of a negatively correlated lncRNA-mRNA pair with ENST00000458993 in a co-expression network, based on microarray analysis of differentially expressed transcripts [Yang et al. DOI:10.4103/1673-5374.247467].