Predicted to enable identical protein binding activity and lipase binding activity. Predicted to be involved in several processes, including negative regulation of peroxisome proliferator activated receptor signaling pathway; positive regulation of triglyceride storage; and regulation of lipid metabolic process. Located in intracellular membrane-bounded organelle and lipid droplet. [provided by Alliance of Genome Resources, Apr 2025]
Forensic Context
A study in mice demonstrated that acute cold exposure (4°C for 4 hours) induced the browning of subcutaneous white adipose tissue, with transcriptional analysis identifying 714 differentially expressed genes, including the upregulation of the PLIN5 gene in cold-treated tissue and its significant upregulation during 3T3-L1 cell browning differentiation [Liang et al. DOI:10.3390/ijms20163968].