Basic Information

Symbol
PPDPF
RNA class
mRNA
Alias
Pancreatic Progenitor Cell Differentiation And Proliferation Factor Exocrine Differentiation And Proliferation Factor DJ697K14.9 C20orf149 Exdpf Pancreatic Progenitor Cell Differentiation And Proliferation Factor Homolog (Zebrafish) Pancreatic Progenitor Cell Differentiation And Proliferation Factor Homolog Chromosome 20 Open Reading Frame 149 EXPDF
Location (GRCh38)
20:63520754-63527076
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Mechanical injury analysis
External database
HGNC NCBI Ensembl UniProt GTEx

MANE select

Transcript ID
NM_024299.4
Sequence length
827.0 nt
GC content
0.6771

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-311.40 kcal/mol
Thermodynamic ensemble
Free energy: -324.98 kcal/mol
Frequency: 0.0000
Diversity: 241.09
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.....((.((((((.(......).)))))))).....((((......))))....((((((.((((.((((((((.((((((..(((((..(((.((((((((.(((((((((((((((..((((((...........(((......))).......))))))...))))))..)))((((((((((((....))))))..(((.(((((((((.(((((.......))))).....((....)).....((((.((((.((((((..((((.......(((.....)))........))))..)))))).))))))))(((((..........(((((.........)))))....))))).))))))))))))..)).))))....(((...)))...))))))..)).)))))).)))..)))))..))((((((....))))))....(((..(((.((...(((((((.(.....).))))))))))))..))).((((.(.((((......)))))))))...)))).)))))))).))))..)))))).........((((...((((.(.((...................................((((.....)))).((((((.....)))).))............(((((.((((((.......((((((((...)))))).))....(((.....(((((.(((.(((((((........)))...((((.....)))).....(((........)))))))))).))).)).))).)))))).)).))).)).).))))...)))).....
Thermodynamic Ensemble Prediction
...,,(({((((((.{......).))))))}}.....{{((......}}||....((((((.((((.((((((((.((((.,.,((({,..({{.,{({((((((,(((((((((((((..((((((.,.........(((......)))......,))))))...))))))..))))||,{,((((((....)))))).......}))))}||{({(((.....,,||,,{{..,.({...,},.}}.||.{{|||||,{{|((((((,{,.,,,|||{{{.{{{.(({(..{,...)),,}})),))).,,,,)))|||,..{{{{{{,...{{|||,|}...,,.,}|||..,.,||||,||||||||||||||{.,|.},.}}}}},.,,},.,,,))|)))}})),||.,||.|))},)})))}|}){(((((....)))))),,}},|}}}}|||||...(((((((.(.....).)))))))..)))},,,|.(({{.{,(((,....,,,)))})))),..)))).)))))))).))))..))))))......|,.{{{{...{{{{.,.((.......{,..........................,,{{.....,,)),||((((.....)))).))..,,,.....,.{{(((.((((((.......,,((((((...)))))).,|,,,.,((....,(({{,.(({.({{((((........)))},,|{((..,||)|,)...,,(((........))).,}},)).))}.)).,,}.)))))).))}.)).)},),))))...)))).....

Transcripts

ID Sequence Length GC content
NM_001353423.2 NCBI
ACCCCGCGCGCGCCUCUCUGUCGUGGCGCGGCUUCCCGCGGUCUUCUCU… 748 nt 0.6778
NM_024299.4 NCBI
ACCCCGCGCGCGCCUCUCUGUCGUGGCGCGGCUUCCCGCGGUCUUCUCU… 827 nt 0.6771
Summary

Predicted to be involved in cell differentiation. Predicted to act upstream of or within TORC1 signaling and liver development. Located in mitochondrion. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in Sprague-Dawley rats demonstrated that the gene Ppdpf was among the top five differentially expressed genes upregulated in the spinal cord at 3 days post-tibial fracture compared to a 0-day control [Deng et al. DOI:10.1038/s41598-025-17561-6].