Basic Information

Symbol
PRB1
RNA class
mRNA
Alias
Proline Rich Protein BstNI Subfamily 1 PRB1M PRB1L PMF PMS PM Basic Salivary Proline-Rich Protein 1 Proline Rich Protein BstNI Subfamily 1 (Gene/Pseudogene) BstNI Type Basic Salivary Proline-Rich Protein 1 Salivary Proline-Rich Protein Parotid Middle Band Protein Salivary Protein Pe
Location (GRCh38)
12:11351823-11355591
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005039.4
Sequence length
1176.0 nt
GC content
0.5740

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-324.80 kcal/mol
Thermodynamic ensemble
Free energy: -347.31 kcal/mol
Frequency: 0.0000
Diversity: 330.95
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((...(((((((((...))))...((.(((((((((((((((..((....((((((((((((((((.((((.((((((...))))))........(((.....)))((.(((.((.......)).)))....)).(((..(((....)))...)))((...((((((......(((....)))......))))))...))...))))))))).))))........(((((.........((((((((.(((.(((..((((..((.....((((...((((....))))....))))....((((......((((...((....))...))))......((...(((((((.....(((....))).....)))))))...))..........))))...........(((((.....(((((..((((......(((((.((....))....((((....(((....)).)....))))....((((.........(((.(((.........(((((..........((((((.....((((..((((..(...((((((...((....((....)).......))...))))))...)..))))..)))).....)))))).((((........((((....(((....)).)....)))).....)))).....((((...((....))...))))............((.(((.....)))))..))))).........))).))).........))))...........)))))......))))..))))).....))))).((....((...((((......((((..((.(((.....)))))...))))......))))...))....))...((((.....((........))......))))...((((((.....((((((((((((............(((...))).))))))))))))........)))))).....))..))))..))))))..))))))...)))))))....))))))).))..))).))))).........)).))))).))......((((...(((((.......((((((....(((((......)))))...))))))....)))))..))))...................))))))))..
Thermodynamic Ensemble Prediction
.(((..,{(((((({(,,.}}}|...{{{((((({,,(({{(,{.,|{,|,,|{((({{(((((((((.((((.((((((...)))))).........,,.,.,,|,,,..{((,,{....,.},}.|||....,.,||{..(((....)))...}}}{{...((((((......(((....)))......))))))...))...}}},}}}}}.},,}........{((((......,(({..(((({.....|||{{,||....|}....(({{...{{{{....||||,,..}}}}....||||,},...((({...{{,...}}...,||}......{,...{((((((.....(((....))},....}}}}}}}...||....{{....||......,,.....|||||.....||||}..,)))......))))).((....||....{{,{...,,{,....||{|,...|||,....|||,..,.,,||||...||,...||....||,,...........((((((.....((((..((((..,...((((((...((...,((....)).....,}}....))))))...}..))))..)))).....)))))).((....||....(({{...,,{{...,||{|,...|}}}....,,,,,...,,||||...||....||....||,......,.....((.(((.....)))))..|||||....{{{{{|...||,...{{....)).,..,,,|,...||||||.......{{{..{|||.....,)))..}||....||...{||{,.....((((..((.(((.....)))))...))))......|||}...||,...}}....||}.,,,,}},,,..,,,||,......}},...((((((.....((((((((((((....,,...|..{{|...))}.))))))))))))........)))))).....||{{||},...)))))}.},})))}..|,,,|||,.,,||||}}}.....,.)}))|,,.},,,,,.,|}.}|}}|,,|,.,,..((((.,.(((((.......{(((({,...{((((......))))}...))))))....)))))..))))...................})))})))..

Transcripts

ID Sequence Length GC content
NM_005039.4 NCBI
AGCACAGAGUUGGGAGUGACUCCAGAGCCUCCUGCAAGAUGCUGUUGAU… 1176 nt 0.5740
Summary

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in human samples demonstrated that the PRB1 was identified in 49 out of 50 saliva samples with 65.31% average sequence coverage and was detected in sensitivity samples up to a 500-fold dilution, as well as in most aged and substrate samples during the validation of a protease-free mass spectrometry assay for body fluid identification [Brown et al. DOI:10.1021/acs.jproteome.5c00711].