Basic Information

Symbol
PRL
RNA class
mRNA
Alias
Prolactin Decidual Prolactin Growth Hormone A1 GHA1
Location (GRCh38)
6:22287244-22302826
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_000948.6
Sequence length
894.0 nt
GC content
0.4911

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-236.40 kcal/mol
Thermodynamic ensemble
Free energy: -254.24 kcal/mol
Frequency: 0.0000
Diversity: 191.70
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((.(((((((((((.....)))))..)))).....(((((...(((((.(................)))))).)).)))((((((((((...((....)).((((((......((((........))))((((((((...(((..........)))))))))))..))))))))).))))))).((((((((((..(((..(((((.....(((......)))..........((((((((...(.(.((((......((((...((.....))((((((..((........))..)))))).....((((((((....((((((((((.....((........)).))))).....(((((((..((....((((.((.......)).)))).((.((((.((....)).)))).))...))..))))))).....)))))...)))))).))....((((.....))))....))))....)))).).)..))))))))........))))).......(((((((((((..(((((.(((((((.....)))).......(((((.((((((((.(.(((((((...((((......))))..))))))).....).))).)))))..)))))))).))))).....)))))).)))))..(((.(((((((..........(((((((....(((((..((.((((.((.(((((............((....)).......((.(((((........))))).))......))))).))...)))).)))))))....)))))))........))))))).)))...)))..)))))))))).................)).))...(((((..........)))))..
Thermodynamic Ensemble Prediction
.,{(((((((((((.....))))}.,}))},{{,,(({{{...{{{{{.|.....||,...}}..,}))))}.|,,}|}|{((((({{,,,,((.{,.||{((((,{......{{{,.||.,,}}))))({((((((...(((..........))))))))})),.,,,)))))).))))))}.((((((((({.{((,,.{,,||,||...||,....,{{{{{{{......((((((((...{.{.((((......((((...((....,),((((((..((........))..)))))).....((((((((....((((((((((...,...........)).))))).....(((((((..({....((((.((.......)).)))).((.((((.({....}).)))).))...})..))))))).....)))))...)))))).))..{,((((.....)))).}}.))))....)))).,.}..))))))))....{{...,)),.....,.(((((((((((.,(((((,(({((((,....}})).......{{{,,.||{{{{{,..,||||||||,,((((......}))).{||||,||{.{{,,..,,}))}})}},,)))))}.}}}}}.....)))))).)))))..(((.(((((((..........(((((((....(((((..((.{(((.((.(((((.............|,...||.......((.(((((........))))).))......))))).))...)))}.)))))))....)))))))......,.))))))).))).}))))}})))))))))),,}...............,.,|,,.,{{||,.........}}},,..

Transcripts

ID Sequence Length GC content
NM_000948.6 NCBI
GUGAGACUUCCAGAUCUUCUCUGGUGAAGUGUGUUUCCUGCAACGAUCA… 894 nt 0.4911
NM_001163558.3 NCBI
AGGUCAUAAGAACCUUCAUUCCAGAAGUACCCUCAAAGACAGAGACACC… 1013 nt 0.4798
Summary

This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues, including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis, and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Aug 2011]

Forensic Context

No relevant information is available at the moment.