Basic Information

Symbol
PSG9
RNA class
mRNA
Alias
Pregnancy Specific Beta-1-Glycoprotein 9 PSGII PSG11 Pregnancy-Specific Beta-1-Glycoprotein 9 Pregnancy-Specific Beta-1 Glycoprotein B PS-Beta-G-11 PS-Beta-G-9 PS-Beta-B PSBG-11 PSBG-9 PS34 Pregnancy-Specific Beta-1-Glycoprotein 11 C-R Domain Pregnancy Specific Beta-1-Glycoprotein 11 Pregnancy-Specific Beta-1-Glycoprotein 11 Pregnancy-Specific Glycoprotein 11 Pregnancy-Specific Glycoprotein 9 Pregnancy-Specific Glycoprotein 7 PSG7
Location (GRCh38)
19:43211791-43269530
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_002784.5
Sequence length
1707.0 nt
GC content
0.4552

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-440.70 kcal/mol
Thermodynamic ensemble
Free energy: -475.13 kcal/mol
Frequency: 0.0000
Diversity: 559.19
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((.(((((..(((((((..(((((..(((...)))....)))))(((((...)))))....(((((.....))))).......(((((..........(((((((((.((((......((((....))).)......)))).)))))))))((((...))))...............(((.......)))...)))))...(((((((((((.((.(((((..(((..((((((..((((.(((.((((((((((((.((((...((((.((((((((.............))))).......))).))))...))))...((((((((.(((((((...)))))))))))))))...........((((......)))).)))))))))......(((..((((...(((((((((.((((.......))))..)))..)))))).))))..)))...................((((((((((((.....(((....)))....)))))...)))))))....(((((((...............)))))))..))).)))...))))..))))))..))).))))).))..)))))).)))))...(((.(((((..((....(((((...))))).....))..))))).)))((((((...)))))).....)))))))....((....))..))))).)))....((.(((.(((......)))...))))).............((((((((...(((..(((((((.((.(((((...)))))(((((.....((...((((((.(((((................................(((((....((((((.(((((..(((((((.........)).)))))..)))((((.......))))(((...(((..((.(((.((..(((.((((((((((......))))...........((((((..........))))))............(((.((.....))..)))......)))))).)))..)).)))))))).))).....)).))))))....(.((.....)).).....)))))..((((.........))))..........(((.(((......))).)))(((((((((((..(((...........)))...))))).....))))))...))))).))))))))...))))).............................(((..((.(((((((.....))))))).)))))........)).))))))).(((....))).....(((((..((...(((((..((((((......)).))))...(((.((((((((..((....))...)))))))).)))...........)))))...))..))))).......((((...(((((((((((....(((...(((((.((((..((..(((((((.((((((((.((((.....))))))))))))....)))))))..))..))))...)))))...)))....)))))))))))(((((..((((((......(((((....))))).........)))))).)))))))))....((((((.(..((((.((...)).))))..).))))))((((.(((((....))))).))))...)))..)))))))).
Thermodynamic Ensemble Prediction
..,{{.(((((,.(({{(((((.(((...})).)))))..{,|{{{|{((((...})))|,,..(((((.....))))).......(((((,,{,{.....(((({{{{{,||((,,,,{{(((({...,,).),,....}})),)))))))}}{({|...}))}..............,{((.......}},...}}}}}|..{{{{{{{{{(({({.,((((,.,,,,{(,(((({.((({(((({(((,,,,,,,|..||||....|||.|}||}}}}.|}}..}}}}}.|}|||||,,,...((({{.,|,..{{||{,.((((((((.{{(((({...})))}||||}|}}}}...........,{{({{{..{|,|,.,|||||}||{,....({{..{(((...(((((({({.(({{.......))}}..})),.)))))).))}}..}}}.,,,....,,,,.....,.((((((((((((...,.({{....}))....)))))...)))))))...{((((,,,...}}}}}.......}}}}|||,.|{,.|||...,,}|,|)}||))..})),|||}}.},||}}|}||{|||}|{,.(((.(((({|,{|,,..(((((...))))).....,},}))))).)))||||{|...}}})))}}},,)))||||....{{....)}|.}}}}}.})}.,||||.{{{.|,,.,|,..,}},,,),}}},,}},.}}}},..{{|{{{,,.,.((({,{{,.,{|||,.(((((...))))),|||,.,}},.}},.{{{|||}|||||...........,...................{{(((,,...((((((.(((((..(((((((..,...,..)).))))}..},.((((.......))))|||...(((..((.(((.((..(((.((((((((((......))))..,,.....,{(({,,{..,},,..,,,||,||,,......,},.,,,,}......}},.,,},.....)))))).)))..)).)))))))).}}}.....}).))))))...}.)))},,..))}},.,..,}}}},.{{{,......,,.,,,,........,,(({,(((,.....}}}.}}}||{|||||{{|.,{((,,.........,})}.,)||||.,,,|}}}}||...,}|||.,||}||||,..,,}||.,{{{,,,..,,,.},,.....,,|,||,,,{,,,..(((((((.....)))))))((((((....(((((,{{,(({,,.(((....}}}...,))}}}.,,{{{{..((((({(((....})),.}))))),})))...((((((((..({....,,...)))))))).))))).....))))))}}|||..,..||,{{,...|},{{{{...(((((((((((.({,{((...(((((.,(((((.(({(((((((.((((((((.((({.....)))}))))))))....})))))))).))})),,...)))))...)))}}..))))))))))){((((..(((({{,,.{,,{{{{|....}}}}}.......,,)))))).))))))}}}..,{(|{{{{.,}}||{|,||,,.,,.,))),}),))))))},||}||{{|||||}}}}},},,},})).}.,))))))),.

Transcripts

ID Sequence Length GC content
NM_001301707.2 NCBI
ACAGAAGGAGGAAGGACAGCACAGCUGACAGCCGUGCUCAGACAGCUUC… 1428 nt 0.4419
NM_001301708.2 NCBI
ACAGAAGGAGGAAGGACAGCACAGCUGACAGCCGUGCUCAGACAGCUUC… 1428 nt 0.4475
NM_001301709.2 NCBI
ACAGAAGGAGGAAGGACAGCACAGCUGACAGCCGUGCUCAGACAGCUUC… 1149 nt 0.4291
NM_001411075.1 NCBI
ACAGAAGGAGGAAGGACAGCACAGCUGACAGCCGUGCUCAGACAGCUUC… 2155 nt 0.4863
NM_002784.5 NCBI
ACAGAAGGAGGAAGGACAGCACAGCUGACAGCCGUGCUCAGACAGCUUC… 1707 nt 0.4552
Summary

The protein encoded by this gene is a member of the pregnancy-specific glycoprotein (PSG) family. This protein family and the closely related carcinoembryonic antigen cell adhesion molecule (CEACAM) gene family are both members of the immunoglobulin superfamily, and are organized as a large gene cluster. This protein is thought to inhibit platelet-fibrinogen interactions. Several studies suggest that reduced serum concentrations of PSGs are associated with fetal growth restrictions, while up-regulation of this gene has been observed in colorectal cancers. Several pseudogenes of this gene are found on chromosome 19. Alternative splicing results in multiple transcript variants that encode multiple protein isoforms. [provided by RefSeq, Sep 2014]

Forensic Context

A study in humans evaluating placental mRNA markers for forensic pregnancy diagnostics found that the PSG9 showed no pregnancy-specific expression pattern in whole blood analysis [Gauvin et al. DOI:10.1007/S00414-008-0315-6].