| ID | Sequence | Length | GC content |
|---|---|---|---|
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 2063 nt | 0.5584 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 1937 nt | 0.5514 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 7761 nt | 0.3833 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 1845 nt | 0.5539 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 1818 nt | 0.5567 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 1971 nt | 0.5611 | |
| GCCUCGCCACCAGAGGUUUCCCAGAGAGGAAGGCGUGGCUCCCUCCCGG… | 2360 nt | 0.5085 |
The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009]
A study in human traumatic brain injury (TBI) patients identified the PTGER3 as one of the top five downregulated mRNAs in brain contusion tissues compared to adjacent tissues, with a log2(fold change) of -3.4536 [Zhang et al. DOI:10.097/WNR.0000000000001756].