Basic Information

Symbol
PTOV1
RNA class
mRNA
Alias
PTOV1 Extended AT-Hook Containing Adaptor Protein Activator Interaction Domain-Containing Protein 2 Prostate Tumor-Overexpressed Gene 1 Protein Prostate Tumor Overexpressed 1 PTOV-1 ACID2
Location (GRCh38)
19:49850735-49860744
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001394010.1
Sequence length
1884.0 nt
GC content
0.6571

Transcripts

ID Sequence Length GC content
NM_001305105.2 NCBI
AGUGGUUCGGCCGCGGCGACCCCACUCCGGCGGCGCGUCCCCCGAGCUU… 1607 nt 0.6546
NM_001305108.2 NCBI
ACCUCGCCACGUCACCGACUGCAAACCUUCAGCUGUCUCAGGCUCGGGU… 1495 nt 0.6194
NM_001364745.2 NCBI
ACCUCGCCACGUCACCGACUGCAAACCUUCAGCUGUCUCAGGCUCGGGU… 1517 nt 0.6124
NM_001364747.2 NCBI
ACCUCGCCACGUCACCGACUGCAAACCUUCAGCUGUCUCAGGCUCGGGU… 1658 nt 0.6267
NM_001364748.2 NCBI
GUGGCUCGCGCGUCUUCCCAGGACUCCCCCGCGCCGGAGAGGCCCGCAG… 1531 nt 0.6395
NM_001364749.2 NCBI
ACCUCGCCACGUCACCGACUGCAAACCUUCAGCUGUCUCAGGCUCGGGU… 1706 nt 0.6295
NM_001364750.2 NCBI
GUGGCUCGCGCGUCUUCCCAGGACUCCCCCGCGCCGGAGAGGCCCGCAG… 1483 nt 0.6365
NM_001394010.1 NCBI
AGUGGUUCGGCCGCGGCGACCCCACUCCGGCGGCGCGUCCCCCGAGCUU… 1884 nt 0.6571
NM_017432.5 NCBI
AGUGGUUCGGCCGCGGCGACCCCACUCCGGCGGCGCGUCCCCCGAGCUU… 1655 nt 0.6568
Summary

This gene encodes a protein that was found to be overexpressed in prostate adenocarcinomas. The encoded protein was found to interact with the lipid raft protein flotillin-1 and shuttle it from the cytoplasm to the nucleus in a cell cycle dependent manner. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2015]

Forensic Context

No relevant information is available at the moment.