Basic Information

Symbol
PTX4
RNA class
mRNA
Alias
Pentraxin 4 C16orf38 Pentraxin 4, Long Long Pentraxin 4 Pentraxin-4 Neuronal Pentraxin-Like Protein C16orf38 Chromosome 16 Open Reading Frame 38
Location (GRCh38)
16:1485886-1488981
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001328608.2
Sequence length
1525.0 nt
GC content
0.6597

Transcripts

ID Sequence Length GC content
NM_001013658.1 NCBI
AUGGGGAGUGGAAACUGGGAGGUCACAGGUCCACCUUGUGGCAGUCGGU… 1422 nt 0.6688
NM_001328608.2 NCBI
GGAGGGAGACUGCUGGGGCCUUGCCGUCUCUCCGGAUGGGUUGCUCGUG… 1525 nt 0.6597
Summary

This gene belongs to the pentraxin superfamily, whose members encode highly conserved multifunctional proteins. The encoded protein, like other members of this family, contains a conserved pentraxin domain at the C-terminus. The highest levels of expression of the protein were observed in bone marrow, small intestine and testes. [provided by RefSeq, Jun 2016]

Forensic Context

A study in mice demonstrated that pentraxin 4 (Ptx4) was identified as a downregulated gene in skeletal muscle following incised injury, showing a 10.254-fold downregulation at 12 hours post-injury in a DNA microarray analysis [Gaballah et al. DOI:10.1016/j.forsciint.2016.06.027].