Basic Information

Symbol
PUDP
RNA class
mRNA
Alias
Pseudouridine 5''-Phosphatase DXF68S1E GS1 Pseudouridine 5'-Phosphatase FAM16AX HDHD1A HDHD1 Haloacid Dehalogenase-Like Hydrolase Domain-Containing Protein 1A Haloacid Dehalogenase-Like Hydrolase Domain-Containing Protein 1 Haloacid Dehalogenase-Like Hydrolase Domain Containing 1A Haloacid Dehalogenase-Like Hydrolase Domain Containing 1 Family With Sequence Similarity 16, Member A, X-Linked Pseudouridine-5'-Monophosphatase Pseudouridine-5'-Phosphatase 5'-PsiMPase Protein GS1 EC 3.1.3.96
Location (GRCh38)
X:6667865-7148165
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Postmortem interval inference
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_012080.5
Sequence length
2103.0 nt
GC content
0.4541

Transcripts

ID Sequence Length GC content
NM_001135565.2 NCBI
ACUUCCUCCUCGCCCCCACCCAGACCCAGAAGGCGCCACCAUGGCGGCG… 2172 nt 0.4572
NM_001178135.2 NCBI
ACUUCCUCCUCGCCCCCACCCAGACCCAGAAGGCGCCACCAUGGCGGCG… 788 nt 0.5508
NM_001178136.2 NCBI
ACUUCCUCCUCGCCCCCACCCAGACCCAGAAGGCGCCACCAUGGCGGCG… 1974 nt 0.4504
NM_012080.5 NCBI
ACUUCCUCCUCGCCCCCACCCAGACCCAGAAGGCGCCACCAUGGCGGCG… 2103 nt 0.4541
Summary

This gene encodes a member of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The encoded protein has no known biological function. This gene has a pseudogene on chromosome 1. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2010]

Forensic Context

A review of proteomics in forensic science notes that the PUDP is a protein marker whose abundance increases post-mortem in early post-mortem interval estimation studies using cerebrospinal fluid from human and animal models [Alex et al. DOI:10.1016/j.scijus.2025.101320].