Basic Information

Symbol
PURA
RNA class
mRNA
Alias
Purine Rich Element Binding Protein A PUR1 PUR-ALPHA PURALPHA Purine-Rich Single-Stranded DNA-Binding Protein Alpha Transcriptional Activator Protein Pur-Alpha NEDRIHF MRD31
Location (GRCh38)
5:140107777-140125619
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_005859.5
Sequence length
11511.0 nt
GC content
0.3643

Transcripts

ID Sequence Length GC content
NM_005859.5 NCBI
AGCGGCGGCUGAGGCGACUGAGGCGGCGGGCGGAGCGGCAGGCGGCGGC… 11511 nt 0.3643
Summary

This gene product is a sequence-specific, single-stranded DNA-binding protein. It binds preferentially to the single strand of the purine-rich element termed PUR, which is present at origins of replication and in gene flanking regions in a variety of eukaryotes from yeasts through humans. Thus, it is implicated in the control of both DNA replication and transcription. Deletion of this gene has been associated with myelodysplastic syndrome and acute myelogenous leukemia. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.