The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009]
Forensic Context
A study in mice and humans demonstrated that the angiogenesis capacity of diabetic foot ulcers was related to the dysregulation of the RAB17 expression in human dermal microvascular endothelial cells (HDMECs) [Cheng et al. DOI:10.1093/burnst/tkae043].