Basic Information
Symbol
RAB17
RNA class
mRNA
Alias
RAB17, Member RAS Oncogene Family
Ras-Related Protein Rab-17
EC 3.6.5.2
Location (GRCh38)
2:237574322-237601623
Forensic tag(s)
Wound age identification
MANE select
Transcript ID
NM_022449.4
Sequence length
1603.0 nt
GC content
0.5889
Transcripts
| ID | Sequence | Length | GC content |
|---|---|---|---|
| GCCCUGAAACCUUCUGGGAGGAGAAGAGGCCUGACCUUGGCGCUGGGGU… | 1603 nt | 0.5889 |
Summary
The Rab subfamily of small GTPases plays an important role in the regulation of membrane trafficking. RAB17 is an epithelial cell-specific GTPase (Lutcke et al., 1993 [PubMed 8486736]).[supplied by OMIM, Oct 2009]
Forensic Context
A study in mice and humans demonstrated that the angiogenesis capacity of diabetic foot ulcers was related to the dysregulation of the RAB17 expression in human dermal microvascular endothelial cells (HDMECs) [Cheng et al. DOI:10.1093/burnst/tkae043].