Basic Information

Symbol
RAB1A
RNA class
mRNA
Alias
RAB1A, Member RAS Oncogene Family YPT1 RAB1 Ras-Related Protein Rab-1A YPT1-Related Protein RAB1, Member RAS Oncogene Family Rab GTPase YPT1 Homolog (Yeast) GTP Binding Protein Rab1a Rab GTPase YPT1 Homolog EC 3.6.5.2
Location (GRCh38)
2:65070696-65130986
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_004161.5
Sequence length
2448.0 nt
GC content
0.3824

Transcripts

ID Sequence Length GC content
NM_004161.5 NCBI
AUUUUGGGUGGAAGCGAUAGCUGAGUGGCGGCGGCUGCUGAUUGUGUUC… 2448 nt 0.3824
NM_015543.2 NCBI
AUUUUGGGUGGAAGCGAUAGCUGAGUGGCGGCGGCUGCUGAUUGUGUUC… 2220 nt 0.3779
Summary

This gene encodes a member of the Ras superfamily of GTPases. Members of the gene family cycle between inactive GDP-bound and active GTP-bound forms. This small GTPase controls vesicle traffic from the endoplasmic reticulum to the Golgi apparatus. Multiple alternatively spliced transcript variants have been identified for this gene which encode different protein isoforms. [provided by RefSeq, Oct 2008]

Forensic Context

A study in mice demonstrated that the RAB1A was down-regulated in brain tissue at 8 hours (0.444-fold) and 24 hours (0.395-fold) following whole-body irradiation with 10 Gy γ-rays, as identified through microarray analysis and validated by real-time quantitative RT-PCR [Zhao et al. DOI:10.1158/1078-0432.CCR-05-2418].