Basic Information

Symbol
RAB30
RNA class
mRNA
Alias
RAB30, Member RAS Oncogene Family Ras-Related Protein Rab-30 EC 3.6.5.2
Location (GRCh38)
11:82973133-83071923
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001286060.2
Sequence length
9859.0 nt
GC content
0.3682

Transcripts

ID Sequence Length GC content
NM_001286059.2 NCBI
AGCUCCAUUGGAUAUGACUGUGCACUGGAGCCGGUUGUGCUGUUCUCUC… 9755 nt 0.3651
NM_001286060.2 NCBI
AUUGUGCUACGGUCUCUCCACCCCCUGCUGCUGCUGGGCUUGCGAUUGC… 9859 nt 0.3682
NM_001286061.1 NCBI
ACUCCUCUCAACCUUUUUGAGGCGGAGAGAGGGGGCUGGGCUGGGAAGG… 9783 nt 0.3668
NM_014488.5 NCBI
AUUGUGCUACGGUCUCUCCACCCCCUGCUGCUGCUGGGCUUGCGAUUGC… 9960 nt 0.3696
Summary

Predicted to enable GTP binding activity and GTPase activity. Involved in Golgi organization. Located in Golgi cisterna; cis-Golgi network; and trans-Golgi network. [provided by Alliance of Genome Resources, Apr 2025]

Forensic Context

A study in human neonates with hypoxic-ischemic encephalopathy (HIE) identified the RAB30 as one of 11 significant genes commonly associated with adverse outcome (death or disability) across cohorts from high-income countries and South Asia, though its expression direction was opposite between populations, being downregulated in the high-income cohort but upregulated in the South Asia cohort in cases with adverse outcomes [Montaldo et al. DOI:10.1001/jamanetworkopen.2023.54433].