Basic Information

Symbol
RAB3B
RNA class
mRNA
Alias
RAB3B, Member RAS Oncogene Family Ras-Related Protein Rab-3B Brain Antigen RAB3B EC 3.6.5.2
Location (GRCh38)
1:51907956-51990700
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_002867.4
Sequence length
12780.0 nt
GC content
0.4469

Transcripts

ID Sequence Length GC content
NM_002867.4 NCBI
AGCCCUCAGGCGCCACUGUGAGGACCUGACCGGACCAGACCAUCCCGCA… 12780 nt 0.4469
Summary

Enables GDP binding activity; GTPase activity; and myosin V binding activity. Involved in several processes, including positive regulation of dopamine uptake involved in synaptic transmission; regulation of synaptic vesicle cycle; and regulation of vesicle size. Located in perinuclear region of cytoplasm and vesicle. Is active in dopaminergic synapse and synaptic vesicle membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the RAB3B exhibited a Gini impurity score of 0, being present in all pure seminal fluid samples and in mixtures containing semen while being absent in mixtures without semen, establishing it as a discriminatory protein for body fluid classification [Shehata et al. DOI:10.1016/j.fsigen.2025.103343].