Basic Information

Symbol
RAB6B
RNA class
mRNA
Alias
RAB6B, Member RAS Oncogene Family Ras-Related Protein Rab-6B Small GTP-Binding Protein Small GTPase RAB6B EC 3.6.5.2
Location (GRCh38)
3:133824235-133895882
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016577.4
Sequence length
5596.0 nt
GC content
0.5079

Transcripts

ID Sequence Length GC content
NM_001363953.1 NCBI
AGGGGGCCGACUGGCGCGGCUCUGGAGAGCGCUCCUCCGCCCCGCGCGC… 5688 nt 0.5084
NM_016577.4 NCBI
ACAGAGCGCAGGCGCCGGCGGAGGAGGCAGGCGGGAGGGGGCCGACUGG… 5596 nt 0.5079
Summary

Enables myosin V binding activity. Involved in Golgi organization and protein localization to Golgi membrane. Located in Golgi membrane; ciliary basal body; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in rhesus macaques demonstrated that chronic ethanol self-administration is associated with broad transcriptomic changes, where the RAB6B was identified as a positively correlated hub gene within a coexpression network in the central nucleus of the amygdala, indicating its role in neural mechanisms related to excessive ethanol consumption [Iancu et al. DOI:10.1111/Adb.12501].