Forensic RNA Knowledge Base

Basic Information

Symbol

RABL2A

RNA class

mRNA

Alias

RAB, Member Of RAS Oncogene Family Like 2A Rab-Like Protein 2A

Location (GRCh38)

2:113627215-113643407

UCSC Genome Browser Search in Marker Scope

Forensic tag(s)

Cause of death analysis

External database

HGNC

NCBI

Ensembl

OMIM

UniProt

GTEx

MANE select

Transcript ID

NM_001306158.2

Sequence length

2141.0 nt

GC content

0.5119

Transcripts

ID	Sequence	Length	GC content
NM_001306158.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2141 nt	0.5119
NM_001306159.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1097 nt	0.5287
NM_001306160.3 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2168 nt	0.5120
NM_001306161.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1953 nt	0.5110
NM_001354405.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2413 nt	0.5172
NM_001354406.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2175 nt	0.5122
NM_001354407.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2171 nt	0.5122
NM_001354408.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2330 nt	0.5159
NM_001354409.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2423 nt	0.5171
NM_001354410.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2172 nt	0.5120

Showing 1 to 10 of 26 entries

Summary

This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Forensic Context

A study in humans identified the RABL2A as a potential biomarker significantly associated with 28-day mortality in sepsis via Mendelian randomization analysis from a low-risk, downregulated gene list [Li et al. DOI:10.1038/s41598-025-99619-z].