Forensic RNA Knowledge Base

Basic Information

Symbol

RABL2A

RNA class

mRNA

Alias

RAB, Member Of RAS Oncogene Family Like 2A Rab-Like Protein 2A

Location (GRCh38)

2:113627215-113643407

UCSC Genome Browser Search in Marker Scope

Forensic tag(s)

Cause of death analysis

External database

HGNC

NCBI

Ensembl

OMIM

UniProt

GTEx

MANE select

Transcript ID

NM_001306158.2

Sequence length

2141.0 nt

GC content

0.5119

Transcripts

ID	Sequence	Length	GC content
NM_001354412.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2145 nt	0.5119
NM_001354413.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2300 nt	0.5157
NM_001354414.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2393 nt	0.5169
NM_001354416.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2142 nt	0.5117
NM_001354417.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1060 nt	0.5217
NM_001354418.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1979 nt	0.5114
NM_001354419.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1983 nt	0.5113
NM_001354421.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1949 nt	0.5110
NM_001354423.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	2108 nt	0.5152
NM_001354424.2 NCBI	GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG…	1946 nt	0.5108

Showing 11 to 20 of 26 entries

Summary

This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Forensic Context

A study in humans identified the RABL2A as a potential biomarker significantly associated with 28-day mortality in sepsis via Mendelian randomization analysis from a low-risk, downregulated gene list [Li et al. DOI:10.1038/s41598-025-99619-z].