Basic Information

Symbol
RABL2A
RNA class
mRNA
Alias
RAB, Member Of RAS Oncogene Family Like 2A Rab-Like Protein 2A
Location (GRCh38)
2:113627215-113643407
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001306158.2
Sequence length
2141.0 nt
GC content
0.5119

Transcripts

ID Sequence Length GC content
NM_001354425.2 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 2194 nt 0.5119
NM_001354426.2 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 2137 nt 0.5119
NM_001354427.2 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 2061 nt 0.5090
NM_001354428.2 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 2058 nt 0.5087
NM_007082.5 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 1094 nt 0.5283
NM_013412.4 NCBI
GGAAGUGGAGUGCGCUGCGGUGCGAGCUGGGCCGGCGGGGUGGUUCGAG… 2138 nt 0.5117
Showing 21 to 26 of 26 entries
Summary

This gene is a member of the RAB gene family which belongs to the RAS GTPase superfamily. The proteins in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways. This gene maps to the site of an ancestral telomere fusion event and may be a subtelomeric gene. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Apr 2015]

Forensic Context

A study in humans identified the RABL2A as a potential biomarker significantly associated with 28-day mortality in sepsis via Mendelian randomization analysis from a low-risk, downregulated gene list [Li et al. DOI:10.1038/s41598-025-99619-z].