Basic Information

Symbol
RAD51B
RNA class
mRNA
Alias
RAD51 Paralog B R51H2 REC2 RAD51L1 DNA Repair Protein RAD51 Homolog 2 RAD51 Homolog B HREC2 RAD51 Homolog B (S. Cerevisiae) RAD51 (S. Cerevisiae)-Like 1 RAD51-Like 1 (S. Cerevisiae) Recombination Repair Protein RAD51-Like Protein 1 RecA-Like Protein Rad51B
Location (GRCh38)
14:67819779-68730218
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_133510.4
Sequence length
1559.0 nt
GC content
0.4484

Transcripts

ID Sequence Length GC content
NM_001321809.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 2169 nt 0.4587
NM_001321810.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 2174 nt 0.4361
NM_001321812.1 NCBI
GGCAUGGGUAGCAAGAAACUAAAACGAGUGGGUUUAUCACAAGAGCUGU… 2938 nt 0.4282
NM_001321814.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 3249 nt 0.4223
NM_001321815.1 NCBI
GACCGUCUGAGUAGACAUCAGAUCCUUACCUGUCAGGACUUUUUAUGUC… 1792 nt 0.4492
NM_001321817.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 1657 nt 0.4478
NM_001321818.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 1273 nt 0.4556
NM_001321819.1 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 2267 nt 0.4663
NM_001321821.2 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 2128 nt 0.4563
NM_002877.6 NCBI
GUUGCUUUGCGGCGUUUUCCGCGGGGAAACUGUGUAAAGGGUGGGGAAA… 1871 nt 0.4281
Showing 1 to 10 of 12 entries
Summary

The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata. [provided by RefSeq, Mar 2016] CIViC Summary for RAD51B Gene

Forensic Context

No relevant information is available at the moment.