Basic Information

Symbol
RBP1
RNA class
mRNA
Alias
Retinol Binding Protein 1 CRBP1 CRBP CRABP-I CRBP-I HCRBP1 CRBPI RBPC Retinol-Binding Protein 1, Cellular Cellular Retinol Binding Protein 1 Cellular Retinol-Binding Protein I Retinol-Binding Protein 1 Cellular Retinol-Binding Protein
Location (GRCh38)
3:139517434-139539829
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Other applications
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_002899.5
Sequence length
807.0 nt
GC content
0.5713

Transcripts

ID Sequence Length GC content
NM_001130992.3 NCBI
AAGCGGGGAGGAGCGACCGCUACAAUGGAUCCUCCCGCAGGCUUUGUGC… 1792 nt 0.5095
NM_001130993.3 NCBI
AAGCGGGGAGGAGCGACCGCUACAAUGGAUCCUCCCGCAGGCUUUGUGC… 1954 nt 0.5118
NM_001365940.2 NCBI
AUUUCCGGGCCGCCCACCACCCGCGUAGCACCGGCAGCCGCUGUCCCGG… 701 nt 0.5506
NM_002899.5 NCBI
AAGCGGGGAGGAGCGACCGCUACAAUGGAUCCUCCCGCAGGCUUUGUGC… 807 nt 0.5713
Summary

This gene encodes the carrier protein involved in the transport of retinol (vitamin A alcohol) from the liver storage site to peripheral tissue. Vitamin A is a fat-soluble vitamin necessary for growth, reproduction, differentiation of epithelial tissues, and vision. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

Forensic Context

A study in mice identified retinol binding protein 1 (RBP1) as a retinoic acid-related transcript with enhanced expression in the nucleus accumbens shell [Crofton et al. DOI:10.1016/J.Neuropharm.2020.108398]. In a separate investigation in mice, radiation exposure from α-particles and γ-rays induced characteristic down-regulation of plasma retinol binding protein 4 (RBP4) in liver, a pattern distinct from chemical hepatotoxicants [Roudkenar et al. DOI:10.1269/jrr.07078].