Basic Information

Symbol
RCC1L
RNA class
mRNA
Alias
RCC1 Like WBSCR16 Williams-Beuren Syndrome Chromosomal Region 16 Protein Williams-Beuren Syndrome Chromosome Region 16 RCC1-Like G Exchanging Factor-Like Protein RCC1-Like Protein
Location (GRCh38)
7:75027122-75074228
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_030798.5
Sequence length
2309.0 nt
GC content
0.5946

Transcripts

ID Sequence Length GC content
NM_001281441.2 NCBI
AGGACUGGUGUUAAGGGUCACGCAAGAUGGCGGCGCCCAGAGGCUGCUG… 1334 nt 0.5915
NM_001363447.2 NCBI
AGGACUGGUGUUAAGGGUCACGCAAGAUGGCGGCGCCCAGAGGCUGCUG… 2543 nt 0.5965
NM_030798.5 NCBI
AGGACUGGUGUUAAGGGUCACGCAAGAUGGCGGCGCCCAGAGGCUGCUG… 2309 nt 0.5946
NM_148842.3 NCBI
AGGACUGGUGUUAAGGGUCACGCAAGAUGGCGGCGCCCAGAGGCUGCUG… 2343 nt 0.5911
Summary

This gene encodes a protein containing regulator of chromosome condensation 1-like repeats. The encoded protein may function as a guanine nucleotide exchange factor. This gene is located in a region of chromosome 7 that is deleted in Williams-Beuren syndrome, a multisystem developmental disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Forensic Context

A study in rats demonstrated that the RCC1L was one of 14 mRNA markers selected in a stepwise Fisher discriminant analysis model to classify wound age into groups of 4–12, 16–24, and 28–48 hours post skeletal muscle contusion [Du et al. DOI:10.1007/s00414-018-01990-2].