Basic Information

Symbol
RDH10
RNA class
mRNA
Alias
Retinol Dehydrogenase 10 SDR16C4 Short Chain Dehydrogenase/Reductase Family 16C Member 4 Retinol Dehydrogenase 10 (All-Trans) Short Chain Dehydrogenase/Reductase Family 16C, Member 4 EC 1.1.1.300 EC 1.1.1.N2 EC 1.1.1
Location (GRCh38)
8:73294602-73325281
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Cause of death analysis Wound age identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_172037.5
Sequence length
3959.0 nt
GC content
0.4814

Transcripts

ID Sequence Length GC content
NM_172037.5 NCBI
AGAGCCGGCCCGGAGCGCUCUGACUUGCAAGCGGGCUGCGCUGCGGAGC… 3959 nt 0.4814
Summary

This gene encodes a retinol dehydrogenase, which converts all-trans-retinol to all-trans-retinal, with preference for NADP as a cofactor. Studies in mice suggest that this protein is essential for synthesis of embryonic retinoic acid and is required for limb, craniofacial, and organ development. [provided by RefSeq, Dec 2011]

Forensic Context

A study in mice demonstrated that the RDH10 mRNA was downregulated in ante-mortem burned skin compared to control tissue [Liu et al. DOI:10.1007/s12024-022-00474-5].