Basic Information

Symbol
REEP6
RNA class
mRNA
Alias
Receptor Accessory Protein 6 DP1L1 Polyposis Locus Protein 1-Like 1 C19orf32 Yip2f TB1 Receptor Expression-Enhancing Protein 6 Deleted In Polyposis 1-Like 1 FLJ25383 Chromosome 19 Open Reading Frame 32 REEP6.1 REEP6.2 TB2L1 RP77
Location (GRCh38)
19:1491034-1497927
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Mixture deconvolution
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_138393.4
Sequence length
1360.0 nt
GC content
0.6537

Transcripts

ID Sequence Length GC content
NM_001329556.3 NCBI
AGGCUGCGGGAAAGCGGUGCGCGUGCAGCGGGGUGGGUGCCCUGGUCCG… 1441 nt 0.6572
NM_138393.4 NCBI
AGGCUGCGGGAAAGCGGUGCGCGUGCAGCGGGGUGGGUGCCCUGGUCCG… 1360 nt 0.6537
Summary

The protein encoded by this gene may be involved in the transport of receptors from the endoplasmic reticulum (ER) to the cell surface. The encoded protein may also play a role in regulating ER membrane structure. This gene is required for the proper development of retinal rods and photoreceptors, with defects in this gene being associated with retinitis pigmentosa 77. [provided by RefSeq, May 2017]

Forensic Context

A study in humans developed a target RNA sequencing assay for body fluid mixture deconvolution, which included the REEP6 as an mRNA marker for semen (SE) identification [Yu et al. DOI:10.1016/j.fsigen.2025.103416].