Basic Information

Symbol
RELL1
RNA class
mRNA
Alias
RELT Like 1 RELT-Like Protein 1 Receptor Expressed In Lymphoid Tissues Like 1 Tmp_locus_29 RELT-Like 1
Location (GRCh38)
4:37590800-37686413
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Time since deposition estimation Drug abuse diagnoses
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_001085400.2
Sequence length
3617.0 nt
GC content
0.4379

Transcripts

ID Sequence Length GC content
NM_001085399.2 NCBI
ACUCGAUCAGCCCGCCGGCUCCGGAGCGGCUCUGCCUUCCCGAGCGCGG… 1322 nt 0.5499
NM_001085400.2 NCBI
ACUCGAUCAGCCCGCCGGCUCCGGAGCGGCUCUGCCUUCCCGAGCGCGG… 3617 nt 0.4379
Summary

Involved in positive regulation of p38MAPK cascade. Located in microtubule cytoskeleton and plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the RELL1 was included as a candidate time-of-day prediction marker in a targeted RNA sequencing panel for bloodstains but its coefficient was zero in the final penalized regression model [Gosch et al. DOI:10.1101/2025.02.03.636230]. In a separate human postmortem brain transcriptomic study, the RELL1 was identified as an OUD-specific hub gene in the dorsolateral prefrontal cortex co-expression network, implicating it as an inflammatory regulator in opioid use disorder [Seney et al. DOI:10.1016/j.biopsych.2021.06.007].