Basic Information

Symbol
RESF1
RNA class
mRNA
Alias
Retroelement Silencing Factor 1 KIAA1551 C12orf35 UTA2-1 GET Gonad Expressed Transcript FLJ20696 FLJ10652 Chromosome 12 Open Reading Frame 35 Uncharacterized Protein C12orf35
Location (GRCh38)
Forensic tag(s)
Other applications

MANE select

Transcript ID
NM_018169.4
Sequence length
6234.0 nt
GC content
0.3784

Transcripts

ID Sequence Length GC content
ACUUGACUUAAACUCUGGGGCCCGGGAGGCCGCCGGUUUUCUCCCCGCU… 6234 nt 0.3784
Summary

Predicted to enable histone binding activity and histone methyltransferase binding activity. Predicted to be involved in transposable element silencing by heterochromatin formation. Predicted to act upstream of or within response to bacterium. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in mice demonstrated that the RESF1 gene was upregulated in common in blood leukocytes across three models of systemic inflammation and injury (trauma/hemorrhage, burn, and LPS infusion) at a 2-hour post-injury time point [Brownstein et al. DOI:10.1152/physiolgenomics.00213.2005].