Basic Information

Symbol
RHCG
RNA class
mRNA
Alias
Rh Family C Glycoprotein PDRC2 RHGK SLC42A3 C15orf6 Rhesus Blood Group Family Type C Glycoprotein Rhesus Blood Group, C Glycoprotein Ammonium Transporter Rh Type C Rh Family Type C Glycoprotein Tumor-Related Protein DRC2 Rh Type C Glycoprotein Rh Glycoprotein Kidney Chromosome 15 Open Reading Frame 6 CDRC2
Location (GRCh38)
15:89471398-89496614
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016321.3
Sequence length
1952.0 nt
GC content
0.5743

Transcripts

ID Sequence Length GC content
NM_001321041.2 NCBI
GAACCGCCCGCUGCCAGCCCGGCCAGGCACCCCUGCAGCAUGGCCUGGA… 1941 nt 0.5739
NM_016321.3 NCBI
GAACCGCCCGCUGCCAGCCCGGCCAGGCACCCCUGCAGCAUGGCCUGGA… 1952 nt 0.5743
Summary

Enables several functions, including ammonium channel activity; ankyrin binding activity; and carbon dioxide transmembrane transporter activity. Involved in ammonium transmembrane transport; intracellular monoatomic ion homeostasis; and transepithelial ammonium transport. Located in apical plasma membrane and basolateral plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A study in humans demonstrated that the RHCG mRNA is abundantly expressed in both saliva and vaginal secretion samples and is cross-reactive with menstrual blood [Yu et al. DOI:10.1016/j.fsigen.2025.103416].