Basic Information

Symbol
RHD
RNA class
mRNA
Alias
Rh Blood Group D Antigen SLC42A5 CD240D DIIIc RhPI RhII Rh4 Blood Group Rh(D) Polypeptide Rhesus D Antigen RHXIII Rh30a RH Rh Blood Group D Antigen Weak D Type 160 Rhesus Blood Group, D Antigen Rh Blood Group Antigen Evans Rhesus D Blood Group Protein Rhesus Blood Group Antigen D Rh Blood Group CcEe Antigen Rhesus System D Polypeptide Rh Blood Group, D Anitgen Rh Blood Group C Antigen RhD Blood Group Antigen Blood Group Protein RHD Blood Group Antigen D RH Polypeptide 2 RhD Glycoprotein Weak RHD Antigen Rh Polypeptide 2 D Antigen (DCS) RhD Polypeptide CD240D Antigen RhD Antigen RHDVA(TT) RhK562-II HDFNRH RHCED RHDel RHPII RhDCw RhPII RH30
Location (GRCh38)
1:25272393-25330445
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
-
External database
HGNC NCBI Ensembl OMIM UniProt GTEx

MANE select

Transcript ID
NM_016124.6
Sequence length
2814.0 nt
GC content
0.4790

Transcripts

ID Sequence Length GC content
NM_001127691.3 NCBI
CUGGUGCUGGUGGAACCCCUGCACAGAGACGGACACAGGAUGAGCUCUA… 2526 nt 0.4766
NM_001282867.1 NCBI
GGUGUUGGAGAGAGGGGUGAUGCCUGGUGCUGGUGGAACCCCUGCACAG… 2833 nt 0.4804
NM_001282868.1 NCBI
GGUGUUGGAGAGAGGGGUGAUGCCUGGUGCUGGUGGAACCCCUGCACAG… 2629 nt 0.4804
NM_001282869.2 NCBI
CUGGUGCUGGUGGAACCCCUGCACAGAGACGGACACAGGAUGAGCUCUA… 2660 nt 0.4805
NM_001282870.1 NCBI
GGUGUUGGAGAGAGGGGUGAUGCCUGGUGCUGGUGGAACCCCUGCACAG… 2763 nt 0.4839
NM_001282871.2 NCBI
CUGGUGCUGGUGGAACCCCUGCACAGAGACGGACACAGGAUGAGCUCUA… 2830 nt 0.4823
NM_001282872.1 NCBI
GGUGUUGGAGAGAGGGGUGAUGCCUGGUGCUGGUGGAACCCCUGCACAG… 2933 nt 0.4855
NM_016124.6 NCBI
CUGGUGCUGGUGGAACCCCUGCACAGAGACGGACACAGGAUGAGCUCUA… 2814 nt 0.4790
Summary

The Rh blood group system is the second most clinically significant of the blood groups, second only to ABO. It is also the most polymorphic of the blood groups, with variations due to deletions, gene conversions, and missense mutations. The Rh blood group includes this gene, which encodes the RhD protein, and a second gene that encodes both the RhC and RhE antigens on a single polypeptide. The two genes, and a third unrelated gene, are found in a cluster on chromosome 1. The classification of Rh-positive and Rh-negative individuals is determined by the presence or absence of the highly immunogenic RhD protein on the surface of erythrocytes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Forensic Context

No relevant information is available at the moment.